SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    5371, 5372, 5373, 5374, 5375, 5376, 5377, 
    5378, 5379, 5380, 5381, 5382, 5383, 
    5384, 5385, 5386, 5387, 5388, 5389, 
    5390, 5391, 5392, 5393, 5394
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "16.81"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "cscart_product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 24,
        "rows_produced_per_join": 4,
        "filtered": "19.99",
        "index_condition": "(`test2_gaseus`.`cscart_product_prices`.`product_id` in (5371,5372,5373,5374,5375,5376,5377,5378,5379,5380,5381,5382,5383,5384,5385,5386,5387,5388,5389,5390,5391,5392,5393,5394))",
        "cost_info": {
          "read_cost": "16.33",
          "eval_cost": "0.48",
          "prefix_cost": "16.81",
          "data_read_per_join": "115"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`test2_gaseus`.`cscart_product_prices`.`lower_limit` = 1) and (`test2_gaseus`.`cscart_product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}

Result

product_id price
5371 0.00000000
5372 0.00000000
5373 0.00000000
5374 0.00000000
5375 0.00000000
5376 0.00000000
5377 0.00000000
5378 0.00000000
5379 0.00000000
5380 0.00000000
5381 0.00000000
5382 0.00000000
5383 0.00000000
5384 0.00000000
5385 0.00000000
5386 0.00000000
5387 0.00000000
5388 0.00000000
5389 0.00000000
5390 0.00000000
5391 0.00000000
5392 0.00000000
5393 0.00000000
5394 0.00000000