SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    12608, 12607, 12606, 12605, 12604, 12603, 
    12602, 12601, 12600, 12599, 12598, 
    12597, 12594, 12595, 12596
  ) 
  AND feature_id IN (627, 628, 553, 625, 624) 
  AND lang_code = 'en'

Query time 0.00262

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "7.29"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "PRIMARY",
      "used_key_parts": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "key_length": "15",
      "rows_examined_per_scan": 18,
      "rows_produced_per_join": 18,
      "filtered": "100.00",
      "using_index_for_skip_scan": true,
      "cost_info": {
        "read_cost": "5.49",
        "eval_cost": "1.80",
        "prefix_cost": "7.29",
        "data_read_per_join": "13K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`test2_gaseus`.`cscart_product_features_values`.`product_id` in (12608,12607,12606,12605,12604,12603,12602,12601,12600,12599,12598,12597,12594,12595,12596)) and (`test2_gaseus`.`cscart_product_features_values`.`feature_id` in (627,628,553,625,624)) and (`test2_gaseus`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}